Mangaluru
Doctors at KMC Hospital have managed to perform a rare surgery of big kidney removal on a 52-year-old woman. The patient was presented with a hugely enlarged abdomen due to enlargement of both kidneys.
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease that can lead to significant disability when complications develop.
In ADPKD, fluid-filled cysts develop most of the time in both the kidneys, which become bigger. It can get infected or can cause bleeding within the cysts. Also, ADPKD can progress to renal failure. The disease can significantly impact the quality of life, doctors said.
Keeping her age in mind, a decision was made to remove her kidneys one kidney at a time, starting with the left kidney. The open surgical method was opted for, as this is preferred considering the 4kg size. The patient underwent surgery uneventfully with coordination between the teams of urology led by Dr Sanman Gowda, Dr Sushanth Kumar from nephrology and Dr Madhusudhan Upadya, and a team from the anaesthesiology department of KMC Hospital, Dr BR Ambedkar Circle. Dr Sanman Gowda, consultant urologist, said, “Features of ADPKD often develop between the ages of 30 and 40, and can eventually lead to kidney failure. In the past, this type was called adult polycystic kidney disease, but children can also develop the disorder. Although it is a disease of the kidneys, it can affect the lungs and liver also. The patient is due for a transplant.
Dr Sushanth Kumar, consultant nephrologist said, mutations in either the PKD1 (16p13) or PKD2 (4q21) genes can cause autosomal dominant polycystic kidney disease; PKD1 gene mutations cause ADPKD type 1, and PKD2 gene mutations cause ADPKD type 2, he said.
